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The vaccines were initially developed for the prevention of infectious diseases with great success. Part of this result is due to germs (viruses, bacteria, parasites, etc) are very different from humans, and thus is relatively easy to “train” the human immune system to react to these foreign agents. The situation is much more complex when it is intended that the same human immune system can discriminate between two human cells, one healthy and another malignant (cancer).
For the past fifteen years has been growing expectation of finding effective cancer treatments based on immune manipulation. This perception shows ups and downs, and perhaps worth comparing with the high expectations placed on research with gene therapy, another “form” star “of cancer research who have experienced difficulties: in both cases, the task is more complex than initially estimated. Some of the pitfalls will help improve the approach, and the truth is that the diversity of investigational products, we appreciate everyone for their results. No scientifically acceptable or would be a general statement of style vaccines are useful “or” not useful “. (more…)
